BRIDGE-INDUCED TRANSLOCATION BETWEEN NUP145 AND TOP2 YEAST GENES MODELS THE GENETIC FUSION BETWEEN THE HUMAN ORTHOLOGS ASSOCIATED WITH ACUTE MYELOID LEUKEMIA

In mammalian organisms liquid tumors such as acute myeloid leukemia (AML) are related to spontaneous chromosomal translocations ensuing in gene fusions.We previously developed a system named bridge-induced translocation (BIT) that allows linking together two different chromosomes exploiting the strong endogenous homologous recombination system of t

The occurrence of an adverse drug event (ADE) has become a serious social concern Bing Accessories of public health.Early detection of ADEs can lower the risk of drug safety as well as the expense of the drug.While post-market spontaneous reports of ADEs remain a cornerstone of pharmacovigilance, most existing signal detection algorithms rely on su

The roles of some cake ingredients - oil, a leavening agent, and inulin - in the structure and physicochemical properties of batter and cakes were studied in four different formulations.Oil played an important role in the batter stability, due to its contribution to increasing batter viscosity and occluding air during STYLING TREATMENT OIL mixing.T

Transportation-based models are widely used to solve real-life problems such as supply chain problems, inventory level problems, business models, management problems, etc.The parameters of these problems have been conventionally measured as deterministic.However, these parameters have vagueness due Horseshoes to the uncertainty in the data sets.Suc

Sporades jaechi sp.nov.from Poum, New Caledonia is newly described and shown to be a member of the monophyletic Sporades subgenus Perileptosporades Deuve, 2010.Sporades millei Giachino and S.schuhi Donabauer are newly recognized as members of the subgenus Perileptosporades, and a key to its species is provided.Although Perileptosporades can be defi